desethyl-N-acetylprocainamide

Base Information

• Chemical Name: desethyl-N-acetylprocainamide
• CAS No.: 72040-49-4
• Molecular Formula: C₁₃H₁₉N₃O₂
• Molecular Weight: 249.313
• Mol file: 72040-49-4.mol

Synonyms:Desethyl-N-acetylprocainamide

Chemical Property of desethyl-N-acetylprocainamide

Chemical Property:

• Vapor Pressure: 1.68E-10mmHg at 25°C
• Boiling Point: 509.6°C at 760 mmHg
• Flash Point: 203.8°C
• Density: 1.127g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of desethyl-N-acetylprocainamide

There total 2 articles about desethyl-N-acetylprocainamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-(acetylamino)benzoic acid (556-08-1) → 4-Acetylamino-N-(2-ethylamino-ethyl)-benzamide (72040-49-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / pyridine / dimethylformamide / 2 h

2: TEA / tetrahydrofuran / 18 h

With pyridine; TEA; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1080/00304949609356555

Reference yield:

N-ethylethane-1,2-diamine (110-72-5) + 4-Acetylamino-benzoic acid pentafluorophenyl ester → 4-Acetylamino-N-(2-ethylamino-ethyl)-benzamide (72040-49-4)

Guidance literature:

With TEA; In tetrahydrofuran; for 18h;

DOI:10.1080/00304949609356555

upstream raw materials:

N-ethylethane-1,2-diamine

p-(acetylamino)benzoic acid

Refernces