l-(R,S,S,S)-benzyl nebivolol hydrochloride

Base Information

Chemical Name:l-(R,S,S,S)-benzyl nebivolol hydrochloride
CAS No.:1224567-85-4
Molecular Formula:C₂₉H₃₁F₂NO₄*ClH
Molecular Weight:532.027
Hs Code.:

Synonyms:l-(R,S,S,S)-benzyl nebivolol hydrochloride

Suppliers and Price of l-(R,S,S,S)-benzyl nebivolol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of l-(R,S,S,S)-benzyl nebivolol hydrochloride

Chemical Property:

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of l-(R,S,S,S)-benzyl nebivolol hydrochloride

There total 2 articles about l-(R,S,S,S)-benzyl nebivolol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₂H₁₅FO₃

: 129050-27-7
(R)-2-benzylamino-1-((S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol

: 1224567-85-4
l-(R,S,S,S)-benzyl nebivolol hydrochloride

Guidance literature:: C₁₂H₁₅FO₃; (R)-2-benzylamino-1-((S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol; In methanol; isopropyl alcohol; at 80 ℃;

With hydrogenchloride; In methanol; water; isopropyl alcohol;

Reference yield:

: 1224567-85-4
l-(R,S,S,S)-benzyl nebivolol hydrochloride

Guidance literature:: With sodium carbonate; In ethanol; for 16h; Reflux;

With hydrogenchloride; In water;

Reference yield: 67.0%

: 1224567-85-4
l-(R,S,S,S)-benzyl nebivolol hydrochloride

: 118457-16-2,118457-14-0,118457-15-1,119365-25-2,119365-23-0,1360598-84-0
nebivolol

Guidance literature:: l-(R,S,S,S)-benzyl nebivolol hydrochloride; With sodium hydroxide; In water; iso-butanol; at 25 ℃; Inert atmosphere;

With formic acid; 5% Pd(II)/C(eggshell); In iso-butanol; at 70 ℃; for 4h;

With sodium hydroxide; In water; iso-butanol;