endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

Base Information

Chemical Name:endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate
CAS No.:75011-45-9
Molecular Formula:C₂₆H₂₃NO₃S₂
Molecular Weight:461.606
Hs Code.:

Synonyms:endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

Suppliers and Price of endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

There total 5 articles about endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 75011-43-7
endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexane

: 124-63-0
methanesulfonyl chloride

: 75011-45-9
endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

Guidance literature:: In pyridine; for 12h; Ambient temperature;
DOI:10.1021/jo01312a013

Reference yield:

: 34250-16-3
3-oxocyclopent-1-ene-1-carbonitrile

: 75011-45-9
endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / diethyl ether / 1080 h / Ambient temperature

2: 1) LDA, 2) HMPA / 1) -78 deg C, 30 min, THF, hexane, 2) room temperature, 1 h

3: 80 percent / NaBH₄ / methanol / 0.75 h / 0 °C

4: 80 percent / pyridine / 12 h / Ambient temperature

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium tetrahydroborate; lithium diisopropyl amide; In pyridine; methanol; diethyl ether;
DOI:10.1021/jo01312a013

Reference yield:

: 75011-39-1
5-cyano-6,6-diphenylbicyclo<3.1.0>hexan-2-one

: 75011-45-9
endo-2-hydroxy-endo-3-(phenylsulfenyl)-5-cyano-6,6-diphenylbicyclo<3.1.0>hexyl methanesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: 1) LDA, 2) HMPA / 1) -78 deg C, 30 min, THF, hexane, 2) room temperature, 1 h

2: 80 percent / NaBH₄ / methanol / 0.75 h / 0 °C

3: 80 percent / pyridine / 12 h / Ambient temperature

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium tetrahydroborate; lithium diisopropyl amide; In pyridine; methanol;
DOI:10.1021/jo01312a013