6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride

Base Information

Chemical Name:6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride
CAS No.:1173694-03-5
Molecular Formula:C₁₄H₁₄N₂O₂*ClH
Molecular Weight:278.738
Hs Code.:

Synonyms:6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride

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Chemical Property of 6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride

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Technology Process of 6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride

There total 1 articles about 6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 1173694-02-4
6-phenylimidazo[1,2-a]pyridine-2-carboxylic acid

: 1173694-03-5
6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; water; at 20 ℃; under 6000.6 Torr;

Reference yield: 59.0%

: 1173694-03-5
6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride

: 15532-75-9
1-(3-Trifluoromethylphenyl)piperazine

: 1048777-06-5
(6-Phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone

Guidance literature:: 6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride; With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

1-(3-Trifluoromethylphenyl)piperazine; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

Reference yield:

: 31252-42-3
4-benzylpyperidine

: 1173694-03-5
6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride

: 1048589-00-9
(4-benzylpiperidin-1-yl)(6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-yl)methanone

Guidance literature:: 6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride; With 4-methyl-morpholine; In N,N-dimethyl acetamide; at 20 ℃;

4-benzylpyperidine; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl acetamide; for 0.25h; Automated synthesis;

4-benzylpyperidine; In N,N-dimethyl acetamide; at 20 ℃; for 16 - 20h; Automated synthesis;