C₁₄H₁₄N₂O₃S

Base Information

• Chemical Name: C₁₄H₁₄N₂O₃S
• CAS No.: 1440421-36-2
• Molecular Formula: C₁₄H₁₄N₂O₃S
• Molecular Weight: 290.343
• Mol file: 1440421-36-2.mol

Synonyms:C₁₄H₁₄N₂O₃S

Chemical Property of C₁₄H₁₄N₂O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₄N₂O₃S

There total 2 articles about C₁₄H₁₄N₂O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

4-bromoohenyl methyl sulfone (3466-32-8) + 2-(2-furyl)-4,5-dihydro-1H-imidazole (40029-93-4) → C14H14N2O3S (1440421-36-2)

Guidance literature:

With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 100 ℃;

DOI:10.2174/1570178611310040002

Reference yield:

furfural (98-01-1) → C14H14N2O3S (1440421-36-2)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / dichloromethane / 0 - 20 °C

2: palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate / toluene / 100 °C

With N-Bromosuccinimide; palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In dichloromethane; toluene; 2: |Buchwald-Hartwig Coupling;

DOI:10.2174/1570178611310040002

Reference yield: 82.0%

C14H14N2O3S (1440421-36-2) → C14H12N2O3S (1440421-59-9)

Guidance literature:

With palladium 10% on activated carbon; In toluene; at 100 ℃; Sealed tube;

DOI:10.2174/1570178611310040002

upstream raw materials:

furfural

4-bromoohenyl methyl sulfone

2-(2-furyl)-4,5-dihydro-1H-imidazole

Downstream raw materials:

C₁₄H₁₂N₂O₃S