N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine

Base Information

• Chemical Name: N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine
• CAS No.: 1253739-55-7
• Molecular Formula: C₂₃H₂₂BrCl₂NO
• Molecular Weight: 479.244

Synonyms:N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine

Chemical Property of N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine

Chemical Property:

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Technology Process of N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine

There total 1 articles about N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-[(4-chlorophenoxy)methyl]-1-[(4-chlorophenyl)methyl]aziridine (1253739-48-8) + benzyl bromide (100-39-0) → N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine (1253739-55-7)

Guidance literature:

In acetonitrile; for 5h; regiospecific reaction; Reflux;

DOI:10.1002/ejoc.201000486

Reference yield: 84.0%

N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine (1253739-55-7) → N-benzyl-N-(4-chlorobenzyl)-N-[2-chloro-3-(4-chlorophenoxy)-propyl]amine (1253739-59-1)

Guidance literature:

With tetrabutyl-ammonium chloride; In acetonitrile; for 3h; Reflux;

DOI:10.1002/ejoc.201000486

Reference yield: 82.0%

N-benzyl-N-[2-bromo-3-(4-chlorophenoxy)propyl]-N-(4-chlorobenzyl)amine (1253739-55-7) → N-benzyl-N-(4-chlorobenzyl)-N-[2-iodo-3-(4-chlorophenoxy)-propyl]amine (1253739-63-7)

Guidance literature:

With sodium iodide; In acetonitrile; for 3h; Reflux;

DOI:10.1002/ejoc.201000486

upstream raw materials:

2-[(4-chlorophenoxy)methyl]-1-[(4-chlorophenyl)methyl]aziridine

benzyl bromide

Downstream raw materials:

N-benzyl-N-(4-chlorobenzyl)-N-[2-chloro-3-(4-chlorophenoxy)-propyl]amine

N-benzyl-N-(4-chlorobenzyl)-N-[2-iodo-3-(4-chlorophenoxy)-propyl]amine

N-benzyl-N-(4-chlorobenzyl)-N-[3-(4-chlorophenoxy)-2-fluoropropyl]amine

2-[N-benzyl-N-(4-chlorobenzyl)amino]-3-(4-chlorophenoxy)-1-fluoropropane

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