4-Hydroxymethyl-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Methyl Ester

Base Information

Chemical Name:4-Hydroxymethyl-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Methyl Ester
CAS No.:1006044-27-4
Molecular Formula:C₁₃H₂₃NO₅
Molecular Weight:273.329
Hs Code.:
Mol file:1006044-27-4.mol

Synonyms:1-tert-butyl 4-methyl 4-(hydroxymethyl)piperidine-1,4-dicarboxylate

Suppliers and Price of 4-Hydroxymethyl-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-tert-Butyl4-Methyl4-(Hydroxymethyl)piperidine-1,4-dicarboxylate
10mg
$ 65.00

Crysdot
1-tert-Butyl4-methyl4-(hydroxymethyl)piperidine-1,4-dicarboxylate 95+%
1g
$ 802.00

Chemenu
1-tert-Butyl4-methyl4-(hydroxymethyl)piperidine-1,4-dicarboxylate 95%
1g
$ 757.00

AK Scientific
1-O-tert-butyl4-O-methyl4-(hydroxymethyl)piperidine-1,4-dicarboxylate
100mg
$ 305.60

Total 3 raw suppliers

Chemical Property of 4-Hydroxymethyl-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Methyl Ester

Chemical Property:

Boiling Point:361.5±27.0 °C(Predicted)
PKA:14.94±0.10(Predicted)
Density:1.142±0.06 g/cm3(Predicted)

Purity/Quality:

≥98% ^*data from raw suppliers

1-tert-Butyl4-Methyl4-(Hydroxymethyl)piperidine-1,4-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Hydroxymethyl-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Methyl Ester

There total 6 articles about 4-Hydroxymethyl-Piperidine-1,4-Dicarboxylic Acid 1-Tert-Butyl Ester 4-Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 1005738-45-3
1-(tert-butoxycarbonyl)-4-(methoxycarbonyl)piperidine-4-carboxylic acid

: 1006044-27-4
1-tert-butyl 4-methyl 4-(hydroxymethyl)piperidine-1,4-dicarboxylate

Guidance literature:: 1-(tert-butoxycarbonyl)-4-(methoxycarbonyl)piperidine-4-carboxylic acid; With N-ethyl-N,N-diisopropylamine; methyl chloroformate; In tetrahydrofuran; at 0 ℃; for 0.0166667h;

With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 ℃; for 1h;

With water; sodium hydrogencarbonate; In tetrahydrofuran; methanol; Saturated solution;

Reference yield:

: C₁₅H₂₃NO₈

: 1006044-27-4
1-tert-butyl 4-methyl 4-(hydroxymethyl)piperidine-1,4-dicarboxylate

Guidance literature:: C₁₅H₂₃NO₈; With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃;

With methanol; In tetrahydrofuran; at 0 ℃; for 1.5h;