Azatadine

Base Information

Chemical Name:Azatadine
CAS No.:3964-81-6
Molecular Formula:C₂₀H₂₂N₂
Molecular Weight:290.408
Hs Code.:2933990090
UNII:94Z39NID6C
DSSTox Substance ID:DTXSID6022636
Nikkaji Number:J8.281C
Wikipedia:Azatadine
Wikidata:Q599160
NCI Thesaurus Code:C77430
Pharos Ligand ID:WKK4BUJ6BC8R
Metabolomics Workbench ID:43026
ChEMBL ID:CHEMBL946
Mol file:3964-81-6.mol

Synonyms:azatadine;azatadine maleate;Idulamine;Idulian;Lergocil;Optimine;Zadine

Suppliers and Price of Azatadine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Azatadine 98+%
50mg
$ 280.00

ApexBio Technology
Azatadine
100mg
$ 284.00

ApexBio Technology
Azatadine
10mg
$ 87.00

American Custom Chemicals Corporation
AZATADINE 95.00%
500MG
$ 1871.10

American Custom Chemicals Corporation
AZATADINE 95.00%
50MG
$ 739.20

American Custom Chemicals Corporation
AZATADINE 95.00%
25MG
$ 382.20

Total 28 raw suppliers

Chemical Property of Azatadine

Chemical Property:

Appearance/Colour:White or off-white crystalline powder
Melting Point:124-126ºC
Boiling Point:450.1 °C at 760 mmHg
PKA:8.74±0.20(Predicted)
Flash Point:226 °C
PSA：16.13000
Density:1.127 g/cm³
LogP:3.64560
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:290.178298710
Heavy Atom Count:22
Complexity:417

Purity/Quality:

97% ^*data from raw suppliers

Azatadine 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCC(=C2C3=CC=CC=C3CCC4=C2N=CC=C4)CC1
Uses Antihistaminic.

Technology Process of Azatadine

There total 9 articles about Azatadine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.5%

: 38092-89-6
N-methyldesloratadine

: 3964-81-6
azatadine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; acetic acid; In ethanol; at 60 ℃; for 20h; Solvent; Temperature; Reagent/catalyst;

Reference yield:

: 3964-73-6
5,6-Dihydro-11H-benzo<5,6>cyclohepta<1,2-b>pyridin-11-one

: 3964-81-6
azatadine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / -40 °C

2: H₂SO₄

With sulfuric acid; In tetrahydrofuran;
DOI:10.1021/jm00105a069

Reference yield:

: 32998-95-1
N-tert-butyl-3-methylpyridine-2-carboxamide

: 3964-81-6
azatadine

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) n-BuLi / 1.) THF, -40 deg C

2: POCl₃ / Heating

3: PPA / Heating

4: tetrahydrofuran / -40 °C

5: H₂SO₄

With n-butyllithium; sulfuric acid; trichlorophosphate; In tetrahydrofuran;
DOI:10.1021/jm00105a069