ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

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Chemical Name:ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate
CAS No.:1259032-16-0
Molecular Formula:C₂₁H₂₃N₃O₅S
Molecular Weight:429.497
Hs Code.:

Synonyms:ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

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Chemical Property of ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

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Technology Process of ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

There total 1 articles about ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1258959-83-9
ethyl 3-{4-cyano-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

: 1259032-16-0
ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

Guidance literature:: With hydroxylamine hydrochloride; sodium hydrogencarbonate; In ethanol; for 19h; Reflux;

Reference yield:

: 1259032-16-0
ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

: 213598-07-3
3-chloro-4-isopropoxy-benzoic acid

: 1258959-87-3
ethyl 3-[4-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indol-7-yl]propanoate

Guidance literature:: 3-chloro-4-isopropoxy-benzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; at 20 ℃; for 1h; Inert atmosphere;

ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate; for 1h;

With tetrabutyl ammonium fluoride; for 48h; Reflux;

Reference yield:

: 258273-31-3
3-cyano-4-isopropoxybenzoic acid

: 1259032-16-0
ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate

: 1258959-96-4
ethyl 3-[4-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indol-7-yl]propanoate

Guidance literature:: 3-cyano-4-isopropoxybenzoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; at 20 ℃; for 1h; Inert atmosphere;

ethyl 3-{4-[(Z)-(hydroxyimino)(amino)methyl]-1-[(4-methylphenyl)sulfonyl]-1H-indol-7-yl}propanoate; for 1h;

With tetrabutyl ammonium fluoride; at 120 ℃; for 1.5h; Microwave irradiation;