Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester
• CAS No.: 88273-93-2
• Molecular Formula: C₂₈H₁₉Cl₂NO₄S
• Molecular Weight: 536.435
• Mol file: 88273-93-2.mol

Synonyms:Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester

Chemical Property of Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester

There total 1 articles about Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-chlorophenyl)indolizine (7496-73-3) + Toluene-4-sulfonic acid 2-chloro-4-chlorocarbonyl-phenyl ester (77823-34-8) → Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester (88273-93-2)

Guidance literature:

In 1,2-dichloro-ethane; at 20 - 50 ℃; for 20h;

Reference yield:

Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester (88273-93-2) → Toluene-4-sulfonic acid 4-[1-bromo-2-(4-chloro-phenyl)-indolizine-3-carbonyl]-2-chloro-phenyl ester

Guidance literature:

With bromine; sodium acetate; In 1,4-dioxane; at 20 - 30 ℃; for 1.5h;

Reference yield:

Toluene-4-sulfonic acid 2-chloro-4-[2-(4-chloro-phenyl)-indolizine-3-carbonyl]-phenyl ester (88273-93-2) → (3-Chloro-4-hydroxy-phenyl)-[2-(4-chloro-phenyl)-indolizin-3-yl]-methanone (77823-43-9)

Guidance literature:

With sodium hydroxide; In methanol; for 20h; Yield given; Heating;

upstream raw materials:

2-(4-chlorophenyl)indolizine

Toluene-4-sulfonic acid 2-chloro-4-chlorocarbonyl-phenyl ester

Downstream raw materials:

(3-Chloro-4-hydroxy-phenyl)-[2-(4-chloro-phenyl)-indolizin-3-yl]-methanone

[3-Chloro-4-(3-dipropylamino-propoxy)-phenyl]-[2-(4-chloro-phenyl)-indolizin-3-yl]-methanone; compound with oxalic acid

[3-Chloro-4-(3-dibutylamino-propoxy)-phenyl]-[2-(4-chloro-phenyl)-indolizin-3-yl]-methanone; compound with oxalic acid

[1-Bromo-2-(4-chloro-phenyl)-indolizin-3-yl]-(3-chloro-4-hydroxy-phenyl)-methanone