6-Chloro-5-Nitropyrimidine-2,4-Diol

Base Information

• Chemical Name: 6-Chloro-5-Nitropyrimidine-2,4-Diol
• CAS No.: 6630-30-4
• Molecular Formula: C4H2ClN3O4
• Molecular Weight: 191.52938
• Hs Code.: 2933599090
• Mol file: 6630-30-4.mol

Synonyms:Uracil,6-chloro-5-nitro- (6CI,8CI);6-Chloro-1,2,3,4-tetrahydro-5-nitro-2,4-dioxopyrimidine;6-Chloro-5-nitrouracil;NSC 60045;6-Chloro-5-nitropyrimidine-2,4(1H,3H)-dione;

Chemical Property of 6-Chloro-5-Nitropyrimidine-2,4-Diol

Chemical Property:

• Vapor Pressure: 1.97E-09mmHg at 25°C
• Refractive Index: 1.621
• Boiling Point: 469.3 °C at 760 mmHg
• Flash Point: 237.6 °C
• PSA: 112.06000
• Density: 1.85 g/cm³
• LogP: 0.97260
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

99% ^*data from raw suppliers

6-Chloro-5-nitropyrimidine-2,4(1H,3H)-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Chloro-5-Nitropyrimidine-2,4-Diol

There total 3 articles about 6-Chloro-5-Nitropyrimidine-2,4-Diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

6-chlorouracil (4270-27-3) → 6-chloro-5-nitropyrimidine-2,4(1H,3H)-dione (6630-30-4)

Guidance literature:

With sulfuric acid; nitric acid; at 0 ℃; for 0.5h;

DOI:10.1039/c9ob01436e

Reference yield:

→ 6-chloro-5-nitropyrimidine-2,4(1H,3H)-dione (6630-30-4)

Guidance literature:

6-Chloruracil, HNO3/H2SO4;

Reference yield:

→ 4-Chlor-5-nitro-2,6-dihydroxy-pyrimidin (6630-30-4)

Guidance literature:

4-Chlor-uracil, HNO3(D:1.5)/36N-H2SO4(anfangs 0grad);

DOI:10.1039/jr9600004768

upstream raw materials:

6-chlorouracil

Downstream raw materials:

5-Nitro-4-methylamino-uracil

6-(benzylamino)-5-nitropyrimidine-2,4(1H,3H)-dione

6-(2-hydroxybenzylamino)-5-nitropyrimidine-2,4(1H,3H)-dione

6-(4-Fluoranilino)-5-nitrouracil