4-Methyl-1-naphthol

Base Information

• Chemical Name: 4-Methyl-1-naphthol
• CAS No.: 10240-08-1
• Molecular Formula: C11H10 O
• Molecular Weight: 158.2
• Hs Code.: 2907199090
• European Community (EC) Number: 233-573-2
• DSSTox Substance ID: DTXSID60145042
• Nikkaji Number: J130.657J
• Wikidata: Q83009399
• Mol file: 10240-08-1.mol

Synonyms:4-Methyl-1-naphthol;4-methylnaphthalen-1-ol;10240-08-1;1-Naphthalenol, 4-methyl-;1-Naphthol, 4-methyl-;EINECS 233-573-2;4-methyl-naphthol;1-Naphthalenol, 4-ethyl-;SCHEMBL773683;DTXSID60145042;MFCD00060344;AKOS006271533;BS-14223;CS-0444441;FT-0692533;EN300-243455;W18575;Z1198149533;2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-3-CARBOXYLICACID

Chemical Property of 4-Methyl-1-naphthol

Chemical Property:

• Vapor Pressure: 0.000335mmHg at 25°C
• Melting Point: 85.8°C
• Refractive Index: 1.5440 (estimate)
• Boiling Point: 310.1°Cat760mmHg
• Flash Point: 150.3°C
• PSA: 20.23000
• Density: 1.144g/cm³
• LogP: 2.85380
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 158.073164938
• Heavy Atom Count: 12
• Complexity: 155

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Methylnaphthalen-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C2=CC=CC=C12)O

Technology Process of 4-Methyl-1-naphthol

There total 48 articles about 4-Methyl-1-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-methyl-3,4-dihydro-2H-naphthalen-1-one (19832-98-5) → 4-methyl-1-naphthol (10240-08-1)

Guidance literature:

With (difluoroboryl)dimethylglyoximatocobalt(II) bis(acetonitrile); boron trifluoride diethyl etherate; 3-cyano-N-methyl-quinolinium perchlorate; In acetonitrile; at 20 ℃; for 0.5h; Irradiation; Inert atmosphere; Flow reactor;

DOI:10.1039/c9cy00753a

Reference yield: 95.0%

(1R,8S)-1-Methyl-11-oxa-tricyclo[6.2.1.02,7]undeca-2(7),3,5,9-tetraene → 4-methyl-1-naphthol (10240-08-1)

Guidance literature:

With dichlorotricarbonylruthenium(II) dimer; In 1,2-dichloro-ethane; at 60 ℃; for 18h; regioselective reaction; Inert atmosphere;

DOI:10.1021/jo901504n

Reference yield: 95.0%

1-methoxy-4-methylnaphthalene (24821-54-3) → 4-methyl-1-naphthol (10240-08-1)

Guidance literature:

With boron tribromide; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/chem.201700667

upstream raw materials:

4-hydroxy-1-naphthaldehyde

1-methoxy-4-methylnaphthalene

pyridine hydrochloride

4-hydroxy-1-methyl-2-naphthoic acid

Downstream raw materials:

1-Hydroxy-4-methyl-5,6,7,8-tetrahydro-naphthalin

3-methylnaphthalen-1-ol

2-(phenylamino)-4-(phenylimino)-1(4H)-naphthalenone

2,2'-dianilino-4H,4'H-4,4'-ethanediylidene-bis-naphthalen-1-one