Pyridine hydrochloride

Base Information

• Chemical Name: Pyridine hydrochloride
• CAS No.: 628-13-7
• Molecular Formula: C5H6ClN
• Molecular Weight: 115.562
• Hs Code.: 29333100
• European Community (EC) Number: 211-027-4
• UNII: 1U87419851
• DSSTox Substance ID: DTXSID6027262
• Wikipedia: Pyridinium_chloride
• Wikidata: Q27252901
• Mol file: 628-13-7.mol

Synonyms:monopyridine phosphate;pyridine;pyridine cyanate;pyridine dinitrate;pyridine diphosphate;pyridine disulfate;pyridine hydride;pyridine hydride (2:1);pyridine hydrochloride;pyridine ion (1-), hydrogen;pyridine ion (1-), lithium salt;pyridine ion (1-), potassium salt;pyridine ion (1-), sodium salt;pyridine ion (2+);pyridine monohydrate;pyridine monophosphate;pyridine monosulfate;pyridine nitrate;pyridine perbromate, 82Br-labeled;pyridine perchlorate;pyridine perchlorate, 2H-labeled;pyridine phosphate;pyridine phosphate (2:1);pyridine sulfate;pyridine sulfate (2:1);pyridine, hydrogen bromide;pyridine, hydrogen fluoride;pyridine, hydrogen iodide

Chemical Property of Pyridine hydrochloride

Chemical Property:

• Appearance/Colour: white to tan crystals
• Vapor Pressure: 22.8mmHg at 25°C
• Melting Point: 145-147 °C(lit.)
• Refractive Index: 1.5304 (estimate)
• Boiling Point: 115.3 °C at 760 mmHg
• Flash Point: 20 °C
• PSA: 12.89000
• Density: 1.34 g/cm3
• LogP: 1.88360
• Storage Temp.: Store below +30°C.
• Sensitive.: Hygroscopic
• Solubility.: ethanol: soluble50mg/mL, clear, colorless to light yellow
• Water Solubility.: 85 g/100 mL
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 115.0188769
• Heavy Atom Count: 7
• Complexity: 30.9

Purity/Quality:

99% ^*data from raw suppliers

Pyridine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, Xi
• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38-22
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Pyridines
• Canonical SMILES: C1=CC=NC=C1.Cl
• Uses: Pyridine Hydrochloride is the hydrochloride salt of pyridine, a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niaci n and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions. Pyridine Hydrochloride is the hydrochloride salt of pyridine, a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions.

Technology Process of Pyridine hydrochloride

There total 135 articles about Pyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.3%

z,z,z-octadeca-6,9,12-trienoyl chloride (54562-14-0) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → pyridine hydrochloride (628-13-7) + tri-γ-linolenin (14465-68-0)

Guidance literature:

With pyridine; dmap; In dichloromethane; at 20 - 35 ℃;

Reference yield: 96.0%

pyridine (110-86-1) → pyridine hydrochloride (628-13-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; Schlenk technique;

DOI:10.1002/anie.202101997

Reference yield: 95.0%

pyridine (110-86-1) → pyridine hydrochloride (628-13-7) + N-sulfonic acid pyridinium chloride

Guidance literature:

With chlorosulfonic acid; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/j.molliq.2013.05.009

upstream raw materials:

pyridine

diethyl ether

(S)-2-Octanol

hydrogen cyanide

Downstream raw materials:

1,4-dichlorobutane

Sudan I

2-chloro-1-(2-nitro-phenyl)-ethanol

(Z)-2-Chloro-but-2-enoic acid

Refernces

• 1、 Smith,Bryant. "-". . p. 841,842. Retrieved 1935.
• 2、 Zang, Hongjun,Lou, Jing,Jiao, Shuolei,Li, Huanxin,Du, Yannan,Wang, Jiao. "Valorization of chitin derived N-acetyl-D-glucosamine into high valuable N-containing 3-acetamido-5-acetylfuran using pyridinium-based ionic liquids". . . Retrieved 2021/02/26.
• 3、 Cornella, Josep,Faber, Teresa,Gómez-Palomino, Alejandro,Ghiazza, Clément. "Deaminative chlorination of aminoheterocycles". . . Retrieved 2021/12/23.