Technology Process of N,N-diallyl-2-chloro-6-(2-furyl)aniline
There total 3 articles about N,N-diallyl-2-chloro-6-(2-furyl)aniline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-allyl-2-chloro-6-(2-furyl)aniline;
With
18-crown-6 ether; potassium hydride;
In
toluene; mineral oil;
at 0 ℃;
for 0.166667h;
Inert atmosphere;
allyl iodid;
In
toluene; mineral oil;
at 20 ℃;
for 5h;
Inert atmosphere;
DOI:10.1016/j.tet.2011.12.079
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 16 h / 60 °C / Inert atmosphere
1.2: 16 h / 20 °C / Inert atmosphere; Saturated solution
2.1: 18-crown-6 ether; potassium hydride / toluene; mineral oil / 0.17 h / 0 °C / Inert atmosphere
2.2: 16 h / 20 °C / Inert atmosphere
3.1: 18-crown-6 ether; potassium hydride / toluene; mineral oil / 0.17 h / 0 °C / Inert atmosphere
3.2: 5 h / 20 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; 18-crown-6 ether; potassium hydride;
In
N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1016/j.tet.2011.12.079
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 18-crown-6 ether; potassium hydride / toluene; mineral oil / 0.17 h / 0 °C / Inert atmosphere
1.2: 16 h / 20 °C / Inert atmosphere
2.1: 18-crown-6 ether; potassium hydride / toluene; mineral oil / 0.17 h / 0 °C / Inert atmosphere
2.2: 5 h / 20 °C / Inert atmosphere
With
18-crown-6 ether; potassium hydride;
In
toluene; mineral oil;
DOI:10.1016/j.tet.2011.12.079
