2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate

Base Information

Chemical Name:2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate
CAS No.:1361414-34-7
Molecular Formula:C₂₀H₁₈N₂O₃S
Molecular Weight:366.441
Hs Code.:

Synonyms:2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate

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Chemical Property of 2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate

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Technology Process of 2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate

There total 2 articles about 2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1361414-32-5
4-(2-bromoacetyl)phenethyl acetate

: 1361413-53-7
N-(bis(4-methoxybenzyl)carbamothioyl)benzamide

: 1361414-34-7
2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate

Guidance literature:: In N,N-dimethyl-formamide; at 85 ℃; for 0.5h; Inert atmosphere;

Reference yield:

: 103-45-7
acetic acid phenethyl ester

: 1361414-34-7
2-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}ethyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: aluminum (III) chloride / dichloromethane / 0 °C

1.2: 1.5 h / 0 °C

2.1: bromine / diethyl ether / 1.5 h / 0 - 20 °C

3.1: N,N-dimethyl-formamide / 0.5 h / 85 °C / Inert atmosphere

With aluminum (III) chloride; bromine; In diethyl ether; dichloromethane; N,N-dimethyl-formamide;