bromo-acetic acid-(N-ethyl-anilide)

Base Information

• Chemical Name: bromo-acetic acid-(N-ethyl-anilide)
• CAS No.: 157837-30-4
• Molecular Formula: C₁₀H₁₂BrNO
• Molecular Weight: 242.115
• Mol file: 157837-30-4.mol

Synonyms:bromo-acetic acid-(N-ethyl-anilide)

Chemical Property of bromo-acetic acid-(N-ethyl-anilide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bromo-acetic acid-(N-ethyl-anilide)

There total 2 articles about bromo-acetic acid-(N-ethyl-anilide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-ethyl-N-phenylamine (103-69-5) + 2-Bromoacetyl bromide (598-21-0) → bromo-acetic acid-(N-ethyl-anilide) (157837-30-4)

Guidance literature:

With diethyl ether;

DOI:10.1021/ja01182a073

Reference yield:

2-bromoacetyl chloride (22118-09-8) + N-ethyl-N-phenylamine (103-69-5) → bromo-acetic acid-(N-ethyl-anilide) (157837-30-4)

Guidance literature:

With dmap; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1021/jm970333f

Reference yield: 91.0%

bromo-acetic acid-(N-ethyl-anilide) (157837-30-4) + triethyl phosphite (122-52-1) → diethyl (2-(ethyl(phenyl)amino)-2-oxoethyl)phosphonate (66325-67-5)

Guidance literature:

With sodium iodide; In N,N-dimethyl-formamide; for 0.025h; Microwave irradiation;

DOI:10.1080/00397911.2010.530377

upstream raw materials:

N-ethyl-N-phenylamine

2-Bromoacetyl bromide

2-bromoacetyl chloride

Downstream raw materials:

diethyl (2-(ethyl(phenyl)amino)-2-oxoethyl)phosphonate

4-(4-chlorobenzoyl)-1-ethyl-3,4-dihydro-2(1H)-quinolinone

3-allylsulfonyl-3-(4-chlorobenzoyl)-N-ethyl-N-phenylpropanamide

3-allylsulfonyl-N-ethyl-N-phenyl-4-oxo-pentanamide