ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

Base Information

Chemical Name:ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate
CAS No.:1072091-02-1
Molecular Formula:C₂₀H₃₅NO₄Si
Molecular Weight:381.588
Hs Code.:

Synonyms:ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

Suppliers and Price of ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

There total 3 articles about ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1072091-03-2
ethyl (2S,3R)-4-hydroxy-2-[(4-methoxyphenyl)amino]-3-methylbutanoate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1072091-02-1
ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 10.5h;

Reference yield:

: 124156-21-4
ethyl (4-methoxyphenylimino)acetate

: 1072091-02-1
ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

Guidance literature:: Multi-step reaction with 3 steps

1: (3R,5R)-5-methyl-3-pyrrolidinecarboxylic acid / dimethyl sulfoxide / 1 h / 20 °C

2: sodium tetrahydroborate / methanol; dimethyl sulfoxide / 0.5 h / 0 °C

3: 1H-imidazole / N,N-dimethyl-formamide / 10.5 h / 20 °C

With 1H-imidazole; sodium tetrahydroborate; (3R,5R)-5-methyl-3-pyrrolidinecarboxylic acid; In methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 409095-87-0
ethyl (2S,3R)-3-formyl-2-(4-methoxyphenylamino)butanoate

: 1072091-02-1
ethyl (3R)-4-{[tert-butyl(dimethyl)silyl]oxy}-N-(4-methoxyphenyl)-L-valinate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol; dimethyl sulfoxide / 0.5 h / 0 °C

2: 1H-imidazole / N,N-dimethyl-formamide / 10.5 h / 20 °C

With 1H-imidazole; sodium tetrahydroborate; In methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;