3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Base Information

• Chemical Name: 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide
• CAS No.: 875587-78-3
• Molecular Formula: C₂₅H₂₁ClN₂O₅S
• Molecular Weight: 496.971

Synonyms:3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Chemical Property of 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide

There total 2 articles about 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2,3,4-trimethoxybenzaldehyde (2103-57-3) + 2-hydrazinocarbonyl-3-chloro-5-phenoxy-benzo(b)thiophene (660394-82-1) → 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide (875587-78-3)

Guidance literature:

In 1,4-dioxane; Heating;

Reference yield:

3-chloro-5-phenoxybenzothiophene-2-carbonyl chloride (122024-72-0) → 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide (875587-78-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / hydrazine hydrate / dioxane / 6 h / Heating

2: 52 percent / dioxane / Heating

With hydrazine hydrate; In 1,4-dioxane;

Reference yield: 55.0%

chloroacetyl chloride (79-04-9) + 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide (875587-78-3) → 3-chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [3-chloro-2-oxo-4-(2,3,4-trimethoxy-phenyl)-azetidin-1-yl]-amide

Guidance literature:

With triethylamine; In 1,4-dioxane; at 20 ℃;

upstream raw materials:

2,3,4-trimethoxybenzaldehyde

2-hydrazinocarbonyl-3-chloro-5-phenoxy-benzo(b)thiophene

3-chloro-5-phenoxybenzothiophene-2-carbonyl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 875587-78-3 3-Chloro-5-phenoxy-benzo[b]thiophene-2-carboxylic acid [1-(2,3,4-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide

Send

Send

Metric Ton KG G Pound L ML

Send

Send