N-{6-Amino-5-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino]-pyrimidin-4-yl}-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-formamide

Base Information

• Chemical Name: N-{6-Amino-5-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino]-pyrimidin-4-yl}-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-formamide
• CAS No.: 198198-24-2
• Molecular Formula: C₂₀H₂₇N₇O₉
• Molecular Weight: 509.476
• Mol file: 198198-24-2.mol

Synonyms:N-{6-Amino-5-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino]-pyrimidin-4-yl}-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-formamide

Chemical Property of N-{6-Amino-5-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino]-pyrimidin-4-yl}-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-formamide

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of N-{6-Amino-5-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino]-pyrimidin-4-yl}-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-formamide

There total 1 articles about N-{6-Amino-5-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino]-pyrimidin-4-yl}-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

4-thiothymidine (7236-57-9) + adenosine (58-61-7) → N-{6-Amino-5-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-ylamino]-pyrimidin-4-yl}-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-formamide (198198-24-2)

Guidance literature:

at 5 ℃; for 234h; Irradiation;

DOI:10.1021/jo971162p

upstream raw materials:

4-thiothymidine

adenosine