4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester

Base Information

Chemical Name:4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester
CAS No.:80613-22-5
Molecular Formula:C₃₂H₃₅NO₈
Molecular Weight:561.632
Hs Code.:

Synonyms:4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester

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Chemical Property of 4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester

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Technology Process of 4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester

There total 3 articles about 4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 80613-19-0
4-Bromomethylphenylacetic acid (4-methoxy)phenacyl ester

: 80613-22-5
4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester

Guidance literature:: With potassium fluoride; In acetonitrile; for 16h;
DOI:10.1055/s-1981-29639

Reference yield:

: 13737-36-5
4-bromophenylacetic acid

: 80613-22-5
4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / KF / acetonitrile / 2 h

2: 98 percent / KF / acetonitrile / 16 h

With potassium fluoride; In acetonitrile;
DOI:10.1055/s-1981-29639

Reference yield:

: 2632-13-5
2-Bromo-4'-methoxyacetophenone

: 80613-22-5
4-(Boc-phenylalanyloxymethyl)-phenylacetic acid (4-methoxy)-phenacyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / KF / acetonitrile / 2 h

2: 98 percent / KF / acetonitrile / 16 h

With potassium fluoride; In acetonitrile;
DOI:10.1055/s-1981-29639