(2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

Base Information

Chemical Name:(2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid
CAS No.:156481-92-4
Molecular Formula:C₂₂H₃₀N₂O₄
Molecular Weight:386.491
Hs Code.:

Synonyms:(2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

Suppliers and Price of (2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

There total 3 articles about (2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63126-47-6
(2S)-2-(methoxymethyl)-1-pyrrolidine

: 156557-88-9
(1R,3R,5R)-2-(benzyloxycarbonyl)-2-azabicyclo<3.3.0>octane-3-carboxylic acid

: 156481-92-4
(2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

Guidance literature:: With 4-methyl-morpholine; chloroformic acid ethyl ester; In ethyl acetate; Yield given; 1.) -15 deg C, 1 h, 2.) r.t., 12 h;

Reference yield:

: 129101-19-5
(all-R)-2-Azabicyclo[3.3.0]octan-3-oic acid benzyl ester p-toluenesulfonate

: 156481-92-4
(2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / 10percent Pd/C / cyclohexene / 4 h / Heating

2: 74 percent / NaHCO₃ / H₂O; toluene / 5 h / Ambient temperature

3: N-methylmorpholine, ClCO₂C₂H₅ / ethyl acetate / 1.) -15 deg C, 1 h, 2.) r.t., 12 h

With 4-methyl-morpholine; chloroformic acid ethyl ester; sodium hydrogencarbonate; palladium on activated charcoal; In water; ethyl acetate; toluene; cyclohexene;

Reference yield:

: 128900-19-6,411232-21-8,726691-28-7
(1R,3R,5R)-2-azabicyclo<3.3.0>octane-3-carboxylic acid

: 156481-92-4
(2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / NaHCO₃ / H₂O; toluene / 5 h / Ambient temperature

2: N-methylmorpholine, ClCO₂C₂H₅ / ethyl acetate / 1.) -15 deg C, 1 h, 2.) r.t., 12 h

With 4-methyl-morpholine; chloroformic acid ethyl ester; sodium hydrogencarbonate; In water; ethyl acetate; toluene;