2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester

Base Information

• Chemical Name: 2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester
• CAS No.: 250717-23-8
• Molecular Formula: C₂₂H₂₆N₄O₆
• Molecular Weight: 442.472
• Mol file: 250717-23-8.mol

Synonyms:2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester

Chemical Property of 2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester

There total 3 articles about 2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

diethyl α-oxoadipate (99683-30-4) + 2-(1-benzylhydrazino)-3-nitropyridine (250717-18-1) → 2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester (250717-23-8)

Guidance literature:

In ethanol; for 16h; Heating;

DOI:10.1002/jhet.5570360405

Reference yield:

2-Chloro-3-nitropyridine (5470-18-8,34515-82-7) → 2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester (250717-23-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / Et₃N / ethanol / 6 h / Heating

2: 58 percent / ethanol / 16 h / Heating

With triethylamine; In ethanol; 1: Substitution / 2: Condensation;

DOI:10.1002/jhet.5570360405

Reference yield:

Benzylhydrazine (555-96-4) → 2-[benzyl-(3-nitro-pyridin-2-yl)-hydrazono]-hexanedioic acid diethyl ester (250717-23-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / Et₃N / ethanol / 6 h / Heating

2: 58 percent / ethanol / 16 h / Heating

With triethylamine; In ethanol; 1: Substitution / 2: Condensation;

DOI:10.1002/jhet.5570360405

upstream raw materials:

diethyl α-oxoadipate

2-(1-benzylhydrazino)-3-nitropyridine

2-Chloro-3-nitropyridine

Benzylhydrazine