1-(3-CHLOROPHENOXY)-2-PROPANONE

Base Information

• Chemical Name: 1-(3-CHLOROPHENOXY)-2-PROPANONE
• CAS No.: 15422-18-1
• Molecular Formula: C9H9 Cl O2
• Molecular Weight: 184.622
• Hs Code.: 2914700090
• Mol file: 15422-18-1.mol

Synonyms:2-Propanone,1-(m-chlorophenoxy)- (8CI); (m-Chlorophenoxy)acetone; NSC 211928

Chemical Property of 1-(3-CHLOROPHENOXY)-2-PROPANONE

Chemical Property:

• Vapor Pressure: 0.00781mmHg at 25°C
• Boiling Point: 268.2°C at 760 mmHg
• Flash Point: 114.2°C
• PSA: 26.30000
• Density: 1.187g/cm³
• LogP: 2.30780

Purity/Quality:

98%min ^*data from raw suppliers

1-(3-Chlorophenoxy)propan-2-one 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-CHLOROPHENOXY)-2-PROPANONE

There total 4 articles about 1-(3-CHLOROPHENOXY)-2-PROPANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.6%

→ 1-(3-chlorophenoxy)propan-2-one (15422-18-1)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 0.5h;

With potassium iodide; In acetone; for 3h; Reflux;

Reference yield: 71.0%

3-monochlorophenol (108-43-0) + acetone (67-64-1) → 1-(3-chlorophenoxy)propan-2-one (15422-18-1)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In water; at 60 ℃; for 8h;

DOI:10.1016/j.tetlet.2017.11.043

Reference yield:

3-monochlorophenol (108-43-0) + chloroacetone (78-95-5) → 1-(3-chlorophenoxy)propan-2-one (15422-18-1)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; Heating;

DOI:10.1039/j39680001311

upstream raw materials:

3-monochlorophenol

chloroacetone

acetone

methyloxirane

Downstream raw materials:

(3-Chlor-phenoxy)-aceton-dimethyl-ketal

Refernces

• 1、 Santhosh Kumar,Ravikumar,Chinna Ashalu,Rajender Reddy. "TBAI/TBHP mediated oxidative cross coupling of ketones with phenols and carboxylic acids: Direct access to benzofurans". supporting information. p. 33 - 37. Retrieved 2017/12/11.