3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine

Base Information

• Chemical Name: 3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine
• CAS No.: 114716-67-5
• Molecular Formula: C₆₈H₁₀₁NO₄
• Molecular Weight: 996.554
• Mol file: 114716-67-5.mol

Synonyms:3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine

Chemical Property of 3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine

There total 6 articles about 3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

benzoyl chloride (98-88-4) + 2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine (109582-79-8) → 3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine (114716-67-5)

Guidance literature:

With dmap; In pyridine; at 20 - 55 ℃; for 25h;

DOI:10.1016/0008-6215(86)84010-1

Reference yield:

benzoyl chloride (98-88-4) + 1-O-trityl-N-tetracosanoyl-4-Z-D-erythro-sphingenine (17673-75-5,98103-18-5,103189-83-9,109582-79-8,132697-81-5) → Benzoic acid (Z)-(R)-1-((S)-1-tetracosanoylamino-2-trityloxy-ethyl)-hexadec-2-enyl ester (103136-38-5,114716-67-5,132697-82-6)

Guidance literature:

With dmap; In pyridine; at 20 ℃; for 18h;

DOI:10.1016/0008-6215(86)84010-1

Reference yield:

N-tetracosanoyl-D-erythro-sphingosine (17673-74-4,26549-48-4,73354-07-1,75171-91-4,98103-17-4,102917-80-6,105089-23-4,121468-19-7,121470-52-8,121470-53-9,130607-51-1,130608-87-6,34435-05-7) → 3-O-benzoyl-2-N-tetracosanoyl-1-O-trityl-4-E-D-erythro-sphingenine (114716-67-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / pyridine / 28 h / 20 - 55 °C

2: 88 percent / 4-dimethylaminopyridine / pyridine / 25 h / 20 - 55 °C

With pyridine; dmap; In pyridine;

DOI:10.1016/0008-6215(86)84010-1

upstream raw materials:

benzoyl chloride

1-O-trityl-N-tetracosanoyl-4-Z-D-erythro-sphingenine

trityl chloride

<2(S),3(R),4Z>-2-tetracosanamido-4-octadecene-1,3-diol

Downstream raw materials:

3-O-benzoyl-2-N-tetracosanoyl-4-E-D-erythro-sphingenine

3-O-benzoyl-2-N-tetracosanoyl-4-Z-D-erythro-sphingenine