Technology Process of (E)-2-styrylcyclopropanecarboxylic acid
There total 6 articles about (E)-2-styrylcyclopropanecarboxylic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(E)-ethyl 2-styrylcyclopropanecarboxylate;
With
water; lithium hydroxide;
In
methanol;
at 70 ℃;
for 1.5h;
With
hydrogenchloride;
In
methanol; water;
at 0 ℃;
pH=6;
- Guidance literature:
-
(E)-methyl 2-styrylcyclopropanecarboxylate;
With
water; sodium hydroxide;
In
tetrahydrofuran; methanol;
at 50 ℃;
for 1h;
With
hydrogenchloride;
In
tetrahydrofuran; methanol; water;
pH=2;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: methanol / 0.25 h / 20 °C
2.1: potassium carbonate / 1,4-dioxane / 16 h / 110 °C
3.1: sodium hydroxide; water / methanol; tetrahydrofuran / 1 h / 50 °C
3.2: pH 2
With
water; potassium carbonate; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; methanol;
