Propanedioic acid, 2-[[(1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl]methyl]-, 1,3-diethyl ester

Base Information

Chemical Name:Propanedioic acid, 2-[[(1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl]methyl]-, 1,3-diethyl ester
CAS No.:135266-72-7
Molecular Formula:C₂₅H₃₄N₂O₄
Molecular Weight:426.556
Hs Code.:
European Community (EC) Number:603-912-2
DSSTox Substance ID:DTXSID801103754

Synonyms:DTXSID801103754;135266-72-7;Propanedioic acid, 2-[[(1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl]methyl]-, 1,3-diethyl ester

Suppliers and Price of Propanedioic acid, 2-[[(1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl]methyl]-, 1,3-diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 4 raw suppliers

Chemical Property of Propanedioic acid, 2-[[(1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl]methyl]-, 1,3-diethyl ester

Chemical Property:

Vapor Pressure:0mmHg at 25°C
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:426.25185757
Heavy Atom Count:31
Complexity:637

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1(CCCN2C1C3=C(CC2)C4=CC=CC=C4N3)CC(C(=O)OCC)C(=O)OCC
Isomeric SMILES:CC[C@]1(CCCN2[C@@H]1C3=C(CC2)C4=CC=CC=C4N3)CC(C(=O)OCC)C(=O)OCC

Technology Process of Propanedioic acid, 2-[[(1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl]methyl]-, 1,3-diethyl ester

There total 8 articles about Propanedioic acid, 2-[[(1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl]methyl]-, 1,3-diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 300661-83-0,135099-82-0
diethyl 15aS-ethyl-2,3,6,11,15,15a-hexahydro-1H,5H-indolo[2,3-a]pyrano[3,2-i]quinolizine-14,14-(13H)-dicarboxylate

: 135266-72-7
(1S,12bS)-1-(2,2'-diethoxycarbonylethyl)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine

Guidance literature:: With palladium on activated charcoal; hydrogen; In N,N-dimethyl-formamide; at 20 ℃; for 9h;

Reference yield: 28.0%

: (+/-)-1-ethyl-1-(2',2'-diethoxycarbonylethyl)-1,2,3,4,6,7-hexahydro-12H-indolo<2,3-a>quinolizin-5-iumperchlorate

: 77793-34-1,89396-79-2,135266-72-7
2-((1R,12bS)-1-Ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-1-ylmethyl)-malonic acid diethyl ester

Guidance literature:: With sodium tetrahydroborate; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)88614-2