benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate

Base Information

Chemical Name:benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate
CAS No.:1402840-86-1
Molecular Formula:C₂₆H₁₉ClN₂O₄
Molecular Weight:458.901
Hs Code.:

Synonyms:benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate

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Chemical Property of benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate

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Technology Process of benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate

There total 3 articles about benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 166408-09-9
benzyl 2-(3-chloro-9H-carbazol-7-yl)propionate

: 62348-20-3
oxazol-4-ylcarbonyl chloride

: 1402840-86-1
benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate

Guidance literature:: With dmap; triethylamine; In acetonitrile; at 20 ℃; for 2h;
DOI:10.1021/jm3011146

Reference yield:

: 53716-49-7,52263-83-9
2-(6-chloro-carbazol-2-yl)-propionic acid

: 1402840-86-1
benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 3 h / 20 °C

2.1: dmap; triethylamine / acetonitrile / 2 h / 20 °C

With dmap; potassium carbonate; triethylamine; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm3011146

Reference yield:

: 100-39-0
benzyl bromide

: 1402840-86-1
benzyl 2-(6-chloro-9-(oxazol-4-ylcarbonyl)-9H-carbazol-2-yl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 3 h / 20 °C

2.1: dmap; triethylamine / acetonitrile / 2 h / 20 °C

With dmap; potassium carbonate; triethylamine; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm3011146