(2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

Base Information

Chemical Name:(2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane
CAS No.:198696-92-3
Molecular Formula:C₂₃H₃₂N₂O₄
Molecular Weight:400.518
Hs Code.:

Synonyms:(2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

Suppliers and Price of (2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

There total 5 articles about (2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 198208-15-0
(2R,3R,4S,5S)-5-[N-(tert-butyloxycarbonyl)amino]-2,3-epoxy-4-hydroxy-1,6-diphenylhexane

: 198696-92-3
(2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

Guidance literature:: With ammonia; In ethanol; at 80 ℃; for 168h;
DOI:10.1021/jo971202p

Reference yield:

: 198208-20-7
(2S,3S,4S,5S)-2-azido-5-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

: 198696-92-3
(2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 12h; under 760 Torr; Yield given;
DOI:10.1021/jo971202p

Reference yield:

: 51987-73-6
(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester

: 198696-92-3
(2S,3S,4S,5S)-5-amino-2-[N-(tert-butyloxycarbonyl)amino]-3,4-dihydroxy-1,6-diphenylhexane

Guidance literature:: Multi-step reaction with 5 steps

1: tetrahydrofuran / -78 °C

2: 50 percent / K₂CO₃ / ethanol / 0.42 h

3: 73 percent / NaBH₄ / methanol / 1 h / 0 °C

4: 70 percent / m-CPBA / CH₂Cl₂ / Ambient temperature

5: 36 percent / MH₃ / ethanol / 168 h / 80 °C

With sodium tetrahydroborate; ammonia; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1021/jo971202p