Technology Process of 6,4'-diacetoxy-5-hydroxy-3-oxa-1,2-diaza-cyclopenta[α]flavone
There total 3 articles about 6,4'-diacetoxy-5-hydroxy-3-oxa-1,2-diaza-cyclopenta[α]flavone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sulfuric acid; acetic acid; sodium nitrite;
In
water;
at 0 - 20 ℃;
for 3h;
DOI:10.1007/s11426-011-4361-4
- Guidance literature:
-
Multi-step reaction with 3 steps
1: nitric acid; acetic acid / 4 h / 50 °C
2: palladium 10% on activated carbon; hydrogen / methanol; dichloromethane / 20 °C / 3750.38 Torr
3: sulfuric acid; acetic acid; sodium nitrite / water / 3 h / 0 - 20 °C
With
sulfuric acid; palladium 10% on activated carbon; hydrogen; nitric acid; acetic acid; sodium nitrite;
In
methanol; dichloromethane; water;
DOI:10.1007/s11426-011-4361-4
- Guidance literature:
-
Multi-step reaction with 5 steps
1: thionyl chloride / methanol; N,N-dimethyl-formamide / 48 h / 0 - 40 °C / Inert atmosphere
2: sodium acetate / N,N-dimethyl-formamide / 48 h / 40 °C
3: nitric acid; acetic acid / 4 h / 50 °C
4: palladium 10% on activated carbon; hydrogen / methanol; dichloromethane / 20 °C / 3750.38 Torr
5: sulfuric acid; acetic acid; sodium nitrite / water / 3 h / 0 - 20 °C
With
thionyl chloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; nitric acid; sodium acetate; acetic acid; sodium nitrite;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1007/s11426-011-4361-4