(2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

Base Information

Chemical Name:(2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate
CAS No.:631915-25-8
Molecular Formula:C₃₀H₃₅NO₇S
Molecular Weight:553.676
Hs Code.:

Synonyms:(2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

Suppliers and Price of (2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

There total 6 articles about (2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 124-63-0
methanesulfonyl chloride

: 631915-23-6
(2R,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol

: 631915-25-8
(2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

Guidance literature:: With pyridine; In dichloromethane; at 25 ℃; for 3h;
DOI:10.1002/hlca.200390248

Reference yield:

: 160549-10-0
2,3,5-tri-O-benzyl-D-arabinofuranose

: 631915-25-8
(2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

Guidance literature:: Multi-step reaction with 6 steps

1: 91 percent / NH₂OH*HCl; NaOMe / methanol

2: 92 percent / pyridine / 25 °C

3: 54 percent / Ph₃P; 1H-imidazole; I₂ / toluene / 2 h / Heating

4: 92 percent / Bu₄NF / toluene / 0.5 h / Heating

5: 73 percent / toluene / 3 h / Heating

6: 94 percent / pyridine / CH₂Cl₂ / 3 h / 25 °C

With pyridine; 1H-imidazole; hydroxylamine hydrochloride; tetrabutyl ammonium fluoride; iodine; sodium methylate; triphenylphosphine; In methanol; dichloromethane; toluene;
DOI:10.1002/hlca.200390248

Reference yield:

: 620946-66-9
(E/Z)-2,3,5-tri-O-benzyl-D-arabinose-oxime

: 631915-25-8
(2S,3aR,4R,5R,6R)-hexahydro-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]pyrrolo[1,2-b]isoxazole-2-methanol methanesulfonate

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / pyridine / 25 °C

2: 54 percent / Ph₃P; 1H-imidazole; I₂ / toluene / 2 h / Heating

3: 92 percent / Bu₄NF / toluene / 0.5 h / Heating

4: 73 percent / toluene / 3 h / Heating

5: 94 percent / pyridine / CH₂Cl₂ / 3 h / 25 °C

With pyridine; 1H-imidazole; tetrabutyl ammonium fluoride; iodine; triphenylphosphine; In dichloromethane; toluene;
DOI:10.1002/hlca.200390248