2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile

Base Information

Chemical Name:2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile
CAS No.:1025769-61-2
Molecular Formula:C₂₃H₁₆FN₃
Molecular Weight:353.399
Hs Code.:

Synonyms:2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile

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Chemical Property of 2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile

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Technology Process of 2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile

There total 1 articles about 2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 1025769-60-1
N'-((1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methylene)-4-methylbenzenesulfonohydrazide

: 107-13-1,25014-41-9
acrylonitrile

: 1025769-61-2
2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile

Guidance literature:: N'-((1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methylene)-4-methylbenzenesulfonohydrazide; With sodium hydroxide; water; In 1,4-dioxane; at 85 ℃; for 1h;

With hydrogenchloride; In 1,4-dioxane; water; pH=4 - 5;

acrylonitrile; In benzene; for 2h; Heating / reflux;

Reference yield: 39.0%

: 1025769-61-2
2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile

: 1025769-63-4
(2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropyl)methanamine trifluoroacetate

Guidance literature:: 2-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-phenylcyclopropanecarbonitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 12h;

With methanol; water; In tetrahydrofuran; diethyl ether;