(alphaS)-alpha-[(2-Formylphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid

Base Information

Chemical Name:(alphaS)-alpha-[(2-Formylphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid
CAS No.:185990-56-1
Molecular Formula:C₁₈H₁₃NO₅
Molecular Weight:323.305
Hs Code.:
DSSTox Substance ID:DTXSID901134289
Nikkaji Number:J1.913.250A

Synonyms:SCHEMBL8085423;DTXSID901134289;185990-56-1;(alphaS)-alpha-[(2-Formylphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid

Suppliers and Price of (alphaS)-alpha-[(2-Formylphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (alphaS)-alpha-[(2-Formylphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:323.07937252
Heavy Atom Count:24
Complexity:522

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CC(C(=O)O)N2C(=O)C3=CC=CC=C3C2=O)C=O
Isomeric SMILES:C1=CC=C(C(=C1)C[C@@H](C(=O)O)N2C(=O)C3=CC=CC=C3C2=O)C=O

Technology Process of (alphaS)-alpha-[(2-Formylphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid

There total 8 articles about (alphaS)-alpha-[(2-Formylphenyl)methyl]-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 908589-91-3
(S)-N,N-phthaloyl-o-cyanophenylalanine

: 185990-56-1
(S)-N,N-phthaloyl-o-formylphenylalanine

Guidance literature:: With pyridine; water; hydrogen; acetic acid; at 50 ℃; for 19h; under 2585.81 Torr;
DOI:10.1021/acsmedchemlett.7b00347

Reference yield: 50.0%

: 185990-56-1
(S)-N,N-phthaloyl-o-formylphenylalanine

Guidance literature:

Reference yield:

: 438470-19-0
methyl 2-(N-succinimidyloxycarbonyl)benzoate

: 185990-56-1
(S)-N,N-phthaloyl-o-formylphenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / aq. acetic acid; pyridine; H₂ / Raney nickel

With pyridine; hydrogen; acetic acid; nickel;
DOI:10.1016/j.bmcl.2007.02.020