Technology Process of 2-<(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl>-4-methoxyphenol
There total 11 articles about 2-<(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl>-4-methoxyphenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis(diphenylphosphino)propanepalladium(II) dichloride; lithium triethylborohydride;
In
tetrahydrofuran;
at -2 ℃;
for 3h;
DOI:10.1055/s-1994-25555
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 95 percent / PBr3 / diethyl ether / -20 °C
2: 80 percent / dimethylformamide / 20 °C
3: 90 percent / t-BuOK / -5 - 0 °C
4: 90 percent / Pd(PPh3)4 / tetrahydrofuran / 25 °C
5: 91 percent / C6H5SH, Cs2CO3 / dimethylformamide / 85 °C
6: 92 percent / LiBHEt3 / PdCl2(dppp) / tetrahydrofuran / 0 °C
With
tetrakis(triphenylphosphine) palladium(0); potassium tert-butylate; phosphorus tribromide; lithium triethylborohydride; caesium carbonate; thiophenol;
bis(diphenylphosphino)propanepalladium(II) dichloride;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 92 percent / Al(Oi-Pr)3 / toluene / 110 °C
2: 90 percent / diethylaniline, pyridine / benzene / 4 h / Ambient temperature
3: 90 percent / Pd(PPh3)4 / tetrahydrofuran / 25 °C
4: 91 percent / C6H5SH, Cs2CO3 / dimethylformamide / 85 °C
5: 92 percent / LiBHEt3 / PdCl2(dppp) / tetrahydrofuran / 0 °C
With
pyridine; tetrakis(triphenylphosphine) palladium(0); aluminum isopropoxide; lithium triethylborohydride; caesium carbonate; thiophenol; N,N-diethylaniline;
bis(diphenylphosphino)propanepalladium(II) dichloride;
In
tetrahydrofuran; N,N-dimethyl-formamide; toluene; benzene;
