1-(5'-O-Benzoyl-3'-deoxypentofuran-2'-ulosyl)uracil

Base Information

Chemical Name:1-(5'-O-Benzoyl-3'-deoxypentofuran-2'-ulosyl)uracil
CAS No.:38359-55-6
Molecular Formula:C16H14 N2 O6
Molecular Weight:330.29216
Hs Code.:
DSSTox Substance ID:DTXSID30191718
Wikidata:Q83064301
Mol file:38359-55-6.mol

Synonyms:1-(5'-O-benzoyl-3'-deoxy-beta-D-glycero-pentafuran-2'-ulosyl)uracil;1-(5'-O-benzoyl-3'-deoxypentofuran-2'-ulosyl)uracil;1-BDGPU

Suppliers and Price of 1-(5'-O-Benzoyl-3'-deoxypentofuran-2'-ulosyl)uracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(5'-O-Benzoyl-3'-deoxypentofuran-2'-ulosyl)uracil

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：107.72000
Density:1.416g/cm³
LogP:0.66250
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:330.08518617
Heavy Atom Count:24
Complexity:581

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC(C1=O)N2C=CC(=O)NC2=O)COC(=O)C3=CC=CC=C3
Isomeric SMILES:C1[C@H](O[C@H](C1=O)N2C=CC(=O)NC2=O)COC(=O)C3=CC=CC=C3

Technology Process of 1-(5'-O-Benzoyl-3'-deoxypentofuran-2'-ulosyl)uracil

There total 9 articles about 1-(5'-O-Benzoyl-3'-deoxypentofuran-2'-ulosyl)uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38431-65-1
1-(5-O-benzoyl-2,3-O-dimesyl-β-D-lyxo-furanosyl) uracil

: 38359-55-6
5'-O-benzoyl-3'-deoxy-2'-keto-β-uridine

: 126187-05-1
5'-O-benzoyl-2',3'-dideoxy-2'-oxo-α-uridine

Guidance literature:: With sodium benzoate; In N,N-dimethyl-formamide; at 110 ℃; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/0040-4020(95)01011-4

Reference yield:

: 38359-53-4
1-(5-O-benzoyl-3-O-mesyl-2-tosyl-β-D-lyxo-furanosyl)uracil

: 38359-55-6
5'-O-benzoyl-3'-deoxy-2'-keto-β-uridine

: 126187-05-1
5'-O-benzoyl-2',3'-dideoxy-2'-oxo-α-uridine

Guidance literature:: With sodium benzoate; In N,N-dimethyl-formamide; at 120 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/0040-4020(95)01011-4

Reference yield:

: 146763-12-4
2',3'-di-O-mesyl-5'-O-trityl-(1-β-D-lyxofuranosyl)uracil

: 38359-55-6
5'-O-benzoyl-3'-deoxy-2'-keto-β-uridine

Guidance literature:: Multi-step reaction with 3 steps

1: neat (no solvent) / 12 h / Heating

2: conc. HCl / tetrahydrofuran; H₂O / 12 h / Heating

3: pyridine / 2 h / Ambient temperature

With hydrogenchloride; In tetrahydrofuran; pyridine; water;
DOI:10.1016/S0040-4020(01)89333-9