146763-12-4Relevant academic research and scientific papers
Reactions of 2′,3′-Di-O-mesyl-lyxo-uridine with secondary amines: First report on the one-pot conversion of mesylated nucleosides to enaminonucleosides and the crystal structure of α-enamine
Sakthivel, Kandasamy,Pathak, Tanmaya,Suresh, Cheravakkattu G.
, p. 13251 - 13260 (2007/10/02)
2′,3′-Di-O-mesyl-5′-O-trityl-lyxo-uridine 1 reacted with secondary amines to produce enaminonucleosides 2a-d and 3a-d. Intermediacy of 2′-ketouridine was essential for the anomerisation and enamine formation to take place. The structure of the β-enamine was established unambiguously by analysing the hydrolysed product and that of α-enamine was proved with the help of crystal structure analysis.
Derivatives of 2′,3′-dithiouridine and [1-β-D-(2,3-dithioxylofuranosyl)]uracil
Johnson, Richard,Joshi, Bhalchandra V.,Neidle, Stephen,Reese, Colin B.,Snook, Chris F.
, p. 8151 - 8154 (2007/10/02)
The synthesis of 2′,3′-di-(4-tolylthio)uridine (5) and {1-β-(=D)-[2,3-di-(4-tolylthio)xylofuranosyl]}uracil (7) from (1-β-(=D)-lyxofuranosyl)uracil (3) and uridine, respectively, is described.
