C₂₁H₂₈N₂O₆

Base Information

Chemical Name:C₂₁H₂₈N₂O₆
CAS No.:1301627-72-4
Molecular Formula:C₂₁H₂₈N₂O₆
Molecular Weight:404.463
Hs Code.:

C<sub>21</sub>H<sub>28</sub>N<sub>2</sub>O<sub>6</sub>

Synonyms:C₂₁H₂₈N₂O₆

Suppliers and Price of C₂₁H₂₈N₂O₆

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₂₁H₂₈N₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₂₁H₂₈N₂O₆

There total 3 articles about C₂₁H₂₈N₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2491-20-5
L-alanine methyl ester hydrochloride

: 340732-79-8
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl) propanoic acid

: 1301627-72-4
C₂₁H₂₈N₂O₆

Guidance literature:: (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl) propanoic acid; With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 ℃; for 0.0833333h; Inert atmosphere;

L-alanine methyl ester hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/ol200861f

Reference yield:

: 949894-57-9
(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl) propanoate

: 1301627-72-4
C₂₁H₂₈N₂O₆

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0 °C / Inert atmosphere

1.2: pH 2 - 3 / Inert atmosphere

2.1: 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/ol200861f

Reference yield:

: 4326-36-7
(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester

: 1301627-72-4
C₂₁H₂₈N₂O₆

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate; potassium iodide / acetone / 24 h / Inert atmosphere; Reflux

2.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0 °C / Inert atmosphere

2.2: pH 2 - 3 / Inert atmosphere

3.1: 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium iodide; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ol200861f