N-Boc-O-2-propyn-1-yl-L-tyrosine

Base Information

Chemical Name:N-Boc-O-2-propyn-1-yl-L-tyrosine
CAS No.:340732-79-8
Molecular Formula:C₁₇H₂₁NO₅
Molecular Weight:319.357
Hs Code.:
DSSTox Substance ID:DTXSID001187700

Synonyms:N-Boc-O-2-propyn-1-yl-L-tyrosine;SCHEMBL14945574;AYUJBJSCNWVBGS-AWEZNQCLSA-N;DTXSID001187700;AKOS030212219;(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-prop-2-ynoxyphenyl)propanoic Acid;CS-0368572;N-[(1,1-Dimethylethoxy)carbonyl]-O-2-propyn-1-yl-L-tyrosine;(S)-2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy) phenyl)propanoic acid

Suppliers and Price of N-Boc-O-2-propyn-1-yl-L-tyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Boc-O-2-propyn-1-yl-L-tyrosine

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:319.14197277
Heavy Atom Count:23
Complexity:451

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)OCC#C)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC=C(C=C1)OCC#C)C(=O)O

Technology Process of N-Boc-O-2-propyn-1-yl-L-tyrosine

There total 7 articles about N-Boc-O-2-propyn-1-yl-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 949894-57-9
(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl) propanoate

: 340732-79-8
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl) propanoic acid

Guidance literature:: (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl) propanoate; With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 5h; Inert atmosphere;

With hydrogenchloride; In water; Inert atmosphere;

Reference yield: 89.0%

: 3978-80-1
Boc-Tyr-OH

: 106-96-7
propargyl bromide

: 340732-79-8
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl) propanoic acid

Guidance literature:: Boc-Tyr-OH; propargyl bromide; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 20h;

With sodium hydroxide; In methanol; at 20 ℃; for 2h;
DOI:10.1002/anie.202016113