4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide

Base Information

Chemical Name:4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide
CAS No.:478403-02-0
Molecular Formula:C₂₂H₂₇IN₂O₅
Molecular Weight:526.371
Hs Code.:

Synonyms:4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide

Chemical Property:

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Technology Process of 4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide

There total 1 articles about 4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 478403-00-8
4-hydroxy-N-(3-iodophenyl)-3-methoxyphenylacetamide

: 34619-03-9
tert-butyldicarbonate

: 1074-82-4
potassium phtalimide

: 74-95-3
1,1-dibromomethane

: 478403-02-0
4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide

Guidance literature:: 4-hydroxy-N-(3-iodophenyl)-3-methoxyphenylacetamide; 1,1-dibromomethane; With potassium hydroxide; tetra(n-butyl)ammonium hydroxide; at 40 ℃; for 18h;

potassium phtalimide; In DMF (N,N-dimethyl-formamide); at 50 ℃; for 18h;

tert-butyldicarbonate; With hydrazine; more than 3 stages;

Reference yield:

: 478403-02-0
4-[2-(tert-butoxycarbonylamino)ethoxy]-N-(3-iodophenyl)-3-methoxyphenylacetamide

: 478403-29-1
4-[2-(tert-butoxycarbonylamino)ethoxy]-3-methoxy-N-(3-phenylphenyl)phenylacetamide

Guidance literature:: With caesium carbonate; phenylboronic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; for 18h; Heating / reflux;