Phthalamic acid, N-(p-fluorophenyl)-

Base Information

Chemical Name:Phthalamic acid, N-(p-fluorophenyl)-
CAS No.:19336-77-7
Molecular Formula:C14H10 F N O3
Molecular Weight:259.237
Hs Code.:2924299090
European Community (EC) Number:665-983-6
NSC Number:109196
DSSTox Substance ID:DTXSID40172932
Nikkaji Number:J50.505F
Wikidata:Q83043003
ChEMBL ID:CHEMBL313937
Mol file:19336-77-7.mol

Synonyms:19336-77-7;2-[(4-fluorophenyl)carbamoyl]benzoic acid;2-[(4-fluoroanilino)carbonyl]benzoic acid;Phthalamic acid, N-(p-fluorophenyl)-;N-(p-Fluorophenyl)phthalamic acid;2-((4-Fluorophenyl)carbamoyl)benzoic acid;Benzoic acid, 2-[[(4-fluorophenyl)amino]carbonyl]-;2-[(4-FLUOROPHENYL)CARBAMOYL]-BENZOIC ACID;Benzoic acid, 2-(((4-fluorophenyl)amino)carbonyl)-;NSC 109196;BRN 2944117;NSC109196;Maybridge1_006468;WLN: QVR BVMR DF;Oprea1_544234;Oprea1_872724;CHEMBL313937;SCHEMBL2700510;HMS559N22;DTXSID40172932;4'-FLUOROPHTHALANILIC ACID;CCG-51231;STK065915;AKOS000319466;NSC-109196;2-((4-Fluorophenyl)carbamoyl)benzoicacid;CS-0269497;SR-01000640542-1;Z57204189

Suppliers and Price of Phthalamic acid, N-(p-fluorophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4'-FLUOROPHTHALANILIC ACID AldrichCPR
1ea
$ 144.00

Matrix Scientific
2-[(4-Fluoroanilino)carbonyl]benzoic acid
500mg
$ 117.00

Matrix Scientific
2-[(4-Fluoroanilino)carbonyl]benzoic acid
1g
$ 180.00

Crysdot
2-((4-Fluorophenyl)carbamoyl)benzoicacid 97%
5g
$ 627.00

Aronis compounds
2-{[(4-fluorophenyl)amino]carbonyl}benzoicacid
1g
$ 171.00

American Custom Chemicals Corporation
2-[(4-FLUOROANILINO)CARBONYL]BENZOIC ACID 95.00%
500MG
$ 795.80

Total 7 raw suppliers

Chemical Property of Phthalamic acid, N-(p-fluorophenyl)-

Chemical Property:

Vapor Pressure:1.07E-05mmHg at 25°C
Boiling Point:356.4°Cat760mmHg
Flash Point:169.4°C
PSA：66.40000
Density:1.4g/cm³
LogP:2.84920
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:259.06447134
Heavy Atom Count:19
Complexity:340

Purity/Quality:

98%min ^*data from raw suppliers

4'-FLUOROPHTHALANILIC ACID AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)F)C(=O)O

Technology Process of Phthalamic acid, N-(p-fluorophenyl)-

There total 3 articles about Phthalamic acid, N-(p-fluorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 85-44-9
phthalic anhydride

: 371-40-4
4-fluoroaniline

: 19336-77-7
2-((4-fluorophenyl)carbamoyl)benzoic acid

Guidance literature:: at 135 ℃; for 0.0333333h; microwave irradiation;
DOI:10.1016/S0960-894X(01)00540-6

Reference yield:

: 88-99-3,73607-73-5
benzene-1,2-dicarboxylic acid

: 19336-77-7
2-((4-fluorophenyl)carbamoyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride / Inert atmosphere

2: sodium dodecyl-sulfate / water; acetonitrile / 1 h / 20 °C / Inert atmosphere

With sodium dodecyl-sulfate; acetic anhydride; In water; acetonitrile;