Technology Process of C28H26O4
There total 5 articles about C28H26O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Methyltriphenylphosphonium bromide;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 1h;
Inert atmosphere;
(4-methoxyphenyl)(3,4,5-trimethoxy-2-(naphthalen-2-yl)phenyl)methanone;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1016/j.ejmech.2012.12.008
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; water / 6 h / 80 °C
2.1: magnesium / tetrahydrofuran / 2 h / 0 - 20 °C
3.1: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C
4.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
4.2: 12 h / -78 - 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; sodium carbonate; magnesium; pyridinium chlorochromate;
In
tetrahydrofuran; ethanol; hexane; dichloromethane; water;
1.1: |Suzuki Coupling / 4.1: |Wittig Olefination / 4.2: |Wittig Olefination;
DOI:10.1016/j.ejmech.2012.12.008
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran / 2 h / 0 - 20 °C
2.1: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C
3.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
3.2: 12 h / -78 - 20 °C / Inert atmosphere
With
n-butyllithium; magnesium; pyridinium chlorochromate;
In
tetrahydrofuran; hexane; dichloromethane;
3.1: |Wittig Olefination / 3.2: |Wittig Olefination;
DOI:10.1016/j.ejmech.2012.12.008
