2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride

Base Information

Chemical Name:2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride
CAS No.:104536-07-4
Molecular Formula:C₁₆H₂₀ClNO*ClH
Molecular Weight:314.255
Hs Code.:

Synonyms:2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride

Chemical Property:

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Technology Process of 2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride

There total 1 articles about 2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7758-89-6
copper(I) chloride

: 6529-53-9
1-(2-bromoethyl)-4-chlorobenzene

: 5291-26-9
2-methylenequinuclidin-3-one

: 104536-07-4
2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride

Guidance literature:: With magnesium; In diethyl ether;

Reference yield: 27.0%

: 629-04-9
1-Bromoheptane

: 104536-07-4
2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride

: 2-[3-(4-Chloro-phenyl)-propyl]-1-heptyl-3-oxo-1-azonia-bicyclo[2.2.2]octane; chloride

Guidance literature:: at 90 ℃; for 24h;
DOI:10.1021/jm00395a014

Reference yield:

: 104536-07-4
2-[3-(4-chlorophenyl)propyl]-1-azabicyclo[2.2.2]octan-3-one hydrochloride

: 110473-52-4
cis-2-<3-(4-chlorophenyl)propyl>-1-azabicyclo<2.2.2>octan-3-ol

Guidance literature:: With ammonium hydroxide; L-Selectride; Yield given. Multistep reaction; 1.) methylene chloride, 2.) THF, -78 deg C;
DOI:10.1021/jm00395a014