Benzenamine, N,N,2,6-tetramethyl-

Base Information

• Chemical Name: Benzenamine, N,N,2,6-tetramethyl-
• CAS No.: 769-06-2
• Deprecated CAS: 63469-00-1
• Molecular Formula: C10H15N
• Molecular Weight: 149.236
• European Community (EC) Number: 829-310-1
• NSC Number: 28985
• UNII: YY9VRY10ND
• DSSTox Substance ID: DTXSID5061114
• Nikkaji Number: J421.531A
• Wikidata: Q81989322
• Mol file: 769-06-2.mol

Synonyms:N,N,2,6-Tetramethylaniline;Benzenamine, N,N,2,6-tetramethyl-;769-06-2;2,6-Xylidine, N,N-dimethyl-;2,6-Dimethyl-N,N-dimethylaniline;N,N,2,6-Tetramethylbenzenamine;N,N-Dimethyl-2,6-dimethylaniline;YY9VRY10ND;NSC 28985;NSC-28985;NSC28985;N,6-dimethylaniline;2, N,N-dimethyl-;UNII-YY9VRY10ND;N,2,6-Tetramethylaniline;SCHEMBL1107763;DTXSID5061114;Benzenamine,N,2,6-tetramethyl-;2,6-dimethyl-N,N-dimethylphenylamine;(2,6-Dimethyl-phenyl)-dimethyl-amine;CS-0256516;EN300-6493781;Z1813097316

Chemical Property of Benzenamine, N,N,2,6-tetramethyl-

Chemical Property:

• Vapor Pressure: 0.338mmHg at 25°C
• Melting Point: -36°C
• Refractive Index: 1.5157 (estimate)
• Boiling Point: 199.6°C at 760 mmHg
• PKA: 6.18±0.36(Predicted)
• Flash Point: 78.9°C
• PSA: 3.24000
• Density: 0.932g/cm³
• LogP: 2.36940
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 149.120449483
• Heavy Atom Count: 11
• Complexity: 110

Purity/Quality:

99.5% ^*data from raw suppliers

N,N,2,6-tetramethylaniline 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=CC=C1)C)N(C)C

Technology Process of Benzenamine, N,N,2,6-tetramethyl-

There total 23 articles about Benzenamine, N,N,2,6-tetramethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,6-dimethylnitrobenzene (81-20-9) → N,N,2,6-tetramethylaniline (769-06-2,63469-00-1)

Guidance literature:

With formic acid; triethylamine; In water; tert-butyl alcohol; at 100 ℃; for 24h;

DOI:10.1002/cctc.201701617

Reference yield: 84.0%

carbon dioxide (124-38-9,18923-20-1) + 2,6-dimethylaniline (87-62-7) → N,N,2,6-tetramethylaniline (769-06-2,63469-00-1)

Guidance literature:

With diphenylsilane; C₂₁H₄₁N₃NiP₂; In acetonitrile; at 120 ℃; for 24h; under 2052.14 Torr; Autoclave;

DOI:10.1039/c8cc05948a

Reference yield: 75.0%

C10H15NO (1247014-56-7) → N,N,2,6-tetramethylaniline (769-06-2,63469-00-1)

Guidance literature:

C₁₀H₁₅NO; With N,N-Dimethylthiocarbamoyl chloride; In dichloromethane; at 20 ℃; for 2h;

In acetonitrile; for 3h; Reflux;

DOI:10.1080/00397910903370634

upstream raw materials:

formaldehyd

N-methyl-2,6-dimethylaniline

phenyltrimethylammonium iodide

dimethyl sulfate

Downstream raw materials:

N-(2,6-dimethylphenyl)-N-methylacetamide

[2,6-Dimethyl-4-(3-methyl-3H-naphtho[1,2-d]imidazol-2-yl)-phenyl]-dimethyl-amine

N-methyl-2,6-dimethylaniline

3,5-dimethyl-4-(dimethylamino)benzaldehyde

Refernces

• 1、 Li, Huaifeng,Gon?alves, Théo P.,Zhao, Qianyi,Gong, Dirong,Lai, Zhiping,Wang, Zhixiang,Zheng, Junrong,Huang, Kuo-Wei. "Diverse catalytic reactivity of a dearomatized PN3P?-nickel hydride pincer complex towards CO2 reduction". supporting information. p. 11395 - 11398. Retrieved 2018/10/20.
• 2、 Sun, Xiaofu,Zhu, Qinggong,Hu, Jiayin,Kang, Xinchen,Ma, Jun,Liu, Huizhen,Han, Buxing. "N, N -Dimethylation of nitrobenzenes with CO2 and water by electrocatalysis". . p. 5669 - 5674. Retrieved 2017/08/01.