C₇H₈O₃S*C₁₆H₁₆FNO₂

Base Information

Chemical Name:C₇H₈O₃S*C₁₆H₁₆FNO₂
CAS No.:874336-37-5
Molecular Formula:C₇H₈O₃S*C₁₆H₁₆FNO₂
Molecular Weight:445.512
Hs Code.:

C<sub>7</sub>H<sub>8</sub>O<sub>3</sub>S*C<sub>16</sub>H<sub>16</sub>FNO<sub>2</sub>

Synonyms:C₇H₈O₃S*C₁₆H₁₆FNO₂

Suppliers and Price of C₇H₈O₃S*C₁₆H₁₆FNO₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Methylbenzenesulfonicacidbenzyl(2R)-2-amino-3-(4-fluorophenyl)propanoate >97%
1g
$ 532.00

Matrix Scientific
4-Methylbenzenesulfonicacidbenzyl(2R)-2-amino-3-(4-fluorophenyl)propanoate >97%
500mg
$ 393.00

Total 1 raw suppliers

Chemical Property of C₇H₈O₃S*C₁₆H₁₆FNO₂

Chemical Property:

Purity/Quality:: 4-Methylbenzenesulfonicacidbenzyl(2R)-2-amino-3-(4-fluorophenyl)propanoate >97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₇H₈O₃S*C₁₆H₁₆FNO₂

There total 1 articles about C₇H₈O₃S*C₁₆H₁₆FNO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.1%

: 18125-46-7
(R)-4-fluorophenylalanine

: 104-15-4
toluene-4-sulfonic acid

: 100-51-6,185532-71-2
benzyl alcohol

: 874336-37-5
C₇H₈O₃S*C₁₆H₁₆FNO₂

Guidance literature:: Inert atmosphere; Reflux;
DOI:10.1021/jm2007062

Reference yield: 99.0%

: 874336-37-5
C₇H₈O₃S*C₁₆H₁₆FNO₂

: 203732-76-7
C₁₆H₁₆FNO₂

Guidance literature:: With sodium carbonate; In water; at 20 ℃; Inert atmosphere;
DOI:10.1021/jm2007062

Reference yield:

: 874336-37-5
C₇H₈O₃S*C₁₆H₁₆FNO₂

: 874336-42-2
(R)-2-((R)-2-((S)-2-(((R)-2-(2-(3-aminopropyl)phenoxy)propyl)-amino)-2-cyclopropyl-N-methylacetamido)propanamido)-3-(4-fluorophenyl)propanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: N,N-diethyl-N-isopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere

2: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C / Inert atmosphere

3: N,N-diethyl-N-isopropylamine; HATU / tetrahydrofuran; dichloromethane / 0 - 20 °C / Inert atmosphere

4: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C / Inert atmosphere

5: hydrogenchloride / 1,4-dioxane; water / 1.5 h / 20 °C / Inert atmosphere

With hydrogenchloride; N,N-diethyl-N-isopropylamine; palladium 10% on activated carbon; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole; HATU; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; ethyl acetate;
DOI:10.1021/jm2007062