Technology Process of C37H49N3O2
There total 6 articles about C37H49N3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
dodecyltriphenylphosphonium bromide;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -15 ℃;
for 0.333333h;
C18H17N3O2;
In
tetrahydrofuran; hexane;
at -15 - 20 ℃;
for 3.25h;
Overall yield = 307 mg;
DOI:10.1016/j.tet.2013.03.057
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium azide / acetonitrile / Molecular sieve
2.1: sodium hydride / tetrahydrofuran / 0.08 h / 0 °C
2.2: 0 - 20 °C / Inert atmosphere
3.1: sodium periodate; 2,6-dimethylpyridine; osmium(VIII) oxide / 1,4-dioxane; water; isopropyl alcohol / 6 h / 20 °C
4.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -15 °C
4.2: 3.25 h / -15 - 20 °C
With
2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; n-butyllithium; sodium azide; sodium hydride;
In
tetrahydrofuran; 1,4-dioxane; hexane; water; isopropyl alcohol; acetonitrile;
4.1: |Wittig Olefination / 4.2: |Wittig Olefination;
DOI:10.1016/j.tet.2013.03.057
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: tetrahydrofuran / 2.75 h / 0 - 20 °C
2.1: titanium(IV) isopropylate; diethyl (2S,3S)-tartrate / dichloromethane / 0.25 h / -20 °C
2.2: 3 h / -20 °C / Molecular sieve
3.1: sodium azide / acetonitrile / Molecular sieve
4.1: sodium hydride / tetrahydrofuran / 0.08 h / 0 °C
4.2: 0 - 20 °C / Inert atmosphere
5.1: sodium periodate; 2,6-dimethylpyridine; osmium(VIII) oxide / 1,4-dioxane; water; isopropyl alcohol / 6 h / 20 °C
6.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -15 °C
6.2: 3.25 h / -15 - 20 °C
With
2,6-dimethylpyridine; titanium(IV) isopropylate; sodium periodate; osmium(VIII) oxide; n-butyllithium; sodium azide; diethyl (2S,3S)-tartrate; sodium hydride;
In
tetrahydrofuran; 1,4-dioxane; hexane; dichloromethane; water; isopropyl alcohol; acetonitrile;
6.1: |Wittig Olefination / 6.2: |Wittig Olefination;
DOI:10.1016/j.tet.2013.03.057
