[5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate

Base Information

• Chemical Name: [5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate
• CAS No.: 1332607-79-0
• Molecular Formula: C₂₁H₂₁NO₇S
• Molecular Weight: 431.466
• Mol file: 1332607-79-0.mol

Synonyms:[5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate

Chemical Property of [5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate

There total 1 articles about [5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

acetic anhydride (108-24-7) + 5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indole-3-carbaldehyde (164261-31-8) → [5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate (1332607-79-0)

Guidance literature:

With indium(III) bromide; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/ejoc.201001309

Reference yield: 78.0%

[5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate (1332607-79-0) → C21H20BrNO7S (1273320-50-5)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; Reflux;

DOI:10.1002/ejoc.201001309

Reference yield:

[5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indol-3-yl]methanediyl diacetate (1332607-79-0) → 5-methyl-9-methoxy-12-phenylsulfonyl-12H-naphtho[1,2-b]carbazole (1137726-40-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Reflux

2: iron(III) chloride / 1,2-dichloro-ethane / 4 h / 85 °C / Inert atmosphere

With iron(III) chloride; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; 1,2-dichloro-ethane;

DOI:10.1002/ejoc.201001309

upstream raw materials:

acetic anhydride

5-methoxy-2-methyl-1-(phenylsulfonyl)-1H-indole-3-carbaldehyde

Downstream raw materials:

C₃₁H₃₀N₂O₃S

5-methyl-9-methoxy-12-phenylsulfonyl-12H-naphtho[1,2-b]carbazole

2,8,9-trimethoxy-5-phenylsulfonyl-5H-benzo[b]carbazole

C₂₁H₂₀BrNO₇S