Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

Base Information

Chemical Name:Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester
CAS No.:173483-70-0
Molecular Formula:C₂₆H₂₈INO₄
Molecular Weight:545.417
Hs Code.:

Synonyms:Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

Suppliers and Price of Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

There total 6 articles about Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 106-95-6
allyl bromide

: 173483-69-7
N-(tert-butyloxycarbonyl)-4-(benzyloxy)-1-iodo-7-methoxy-2-naphthylamine

: 173483-70-0
Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; paraffin; 1.) 0 deg C, 45 min, 2.) 25 deg C, 3 h;
DOI:10.1021/jo952033g

Reference yield:

: 100-39-0
benzyl bromide

: 173483-70-0
Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / K₂CO₃, Bu₄NI / dimethylformamide / 5 h / 25 °C

2: 95 percent / LiOH, H₂O / tetrahydrofuran; methanol / 18 h / 23 °C

3: 68 percent / DPPA, Et₃N / 10 h / Heating

4: 89 percent / TsOH, NIS / tetrahydrofuran; methanol / 3 h / -78 °C

5: 93 percent / NaH / dimethylformamide; paraffin / 1.) 0 deg C, 45 min, 2.) 25 deg C, 3 h

With lithium hydroxide; N-iodo-succinimide; diphenyl-phosphinic acid; water; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; paraffin;
DOI:10.1021/jo952033g

Reference yield:

: 173483-53-9
ethyl 1-hydroxy-6-methoxynaphthalene-3-carboxylate

: 173483-70-0
Allyl-(4-benzyloxy-1-iodo-7-methoxy-naphthalen-2-yl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / K₂CO₃, Bu₄NI / dimethylformamide / 5 h / 25 °C

2: 95 percent / LiOH, H₂O / tetrahydrofuran; methanol / 18 h / 23 °C

3: 68 percent / DPPA, Et₃N / 10 h / Heating

4: 89 percent / TsOH, NIS / tetrahydrofuran; methanol / 3 h / -78 °C

5: 93 percent / NaH / dimethylformamide; paraffin / 1.) 0 deg C, 45 min, 2.) 25 deg C, 3 h

With lithium hydroxide; N-iodo-succinimide; diphenyl-phosphinic acid; water; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; paraffin;
DOI:10.1021/jo952033g