4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

Base Information

Chemical Name:4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone
CAS No.:93958-43-1
Molecular Formula:C₁₉H₂₂N₄O₄
Molecular Weight:370.408
Hs Code.:

Synonyms:4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

Chemical Property:

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Technology Process of 4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

There total 4 articles about 4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 93958-41-9
4-chloro-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

: 93958-43-1
4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

Guidance literature:: In dimethyl sulfoxide; at 100 ℃;

Reference yield:

: 31545-27-4
4-chloro-4'-methoxy-3-nitrobenzophenone

: 93958-43-1
4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

Guidance literature:: Multi-step reaction with 3 steps

1: 55 percent / pyridine hydrochloride / 0.5 h / 220 - 230 °C

2: 38 percent / ethanol; H₂O / 8 h / 60 °C

3: 60 percent / dimethylsulfoxide / 100 °C

With pyridine hydrochloride; In ethanol; water; dimethyl sulfoxide;

Reference yield:

: 109-01-3
1-methyl-piperazine

: 93958-43-1
4-amino-4'-hydroxy-3'-(4-methylpiperazin-1-yl)methyl-3-nitrobenzophenone

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / ethanol; H₂O / 8 h / 60 °C

2: 60 percent / dimethylsulfoxide / 100 °C

In ethanol; water; dimethyl sulfoxide;