1-Adamantyl diazomethyl ketone

Base Information

Chemical Name:1-Adamantyl diazomethyl ketone
CAS No.:5934-69-0
Molecular Formula:C12H16N2O
Molecular Weight:204.272
Hs Code.:
DSSTox Substance ID:DTXSID001311422
Nikkaji Number:J1.318.761D

Synonyms:1-Adamantacoyldiazomethane;Damantoyldiazomethane;1-Adamantyl diazomethyl ketone;(1-Adamantanecarbonyl)diazomethane;BRN 2053233;5934-69-0;Ketone, 1-adamantyl diazomethyl;Ethanone, 2-diazo-1-tricyclo(3.3.1.1(3,7))dec-1-yl-;adamantanoyldiazomethane;1-Adamantanoyldiazomethane;1-(Diazoacetyl)adamantane;DTXSID001311422;LS-87026;Ethanone, 2-diazo-1-tricyclo(3.3.1.1(3,7))dec-1-yl- (9CI)

Suppliers and Price of 1-Adamantyl diazomethyl ketone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-Adamantyl diazomethyl ketone

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:204.126263138
Heavy Atom Count:15
Complexity:313

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2CC3CC1CC(C2)(C3)C(=O)C=[N+]=[N-]

Technology Process of 1-Adamantyl diazomethyl ketone

There total 6 articles about 1-Adamantyl diazomethyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 2094-72-6
1-Adamantanecarbonyl chloride

: 5934-69-0
1-(1-adamantyl)-2-diazo-1-ethanone

Guidance literature:: In diethyl ether; addition at -10 deg C (30 min) than r.t., 12 h;
DOI:10.1016/S0040-4020(01)89498-9

Reference yield: 85.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 828-51-3
1-Adamantanecarboxylic acid

: 5934-69-0
1-(1-adamantyl)-2-diazo-1-ethanone

Guidance literature:: 1-Adamantanecarboxylic acid; With methanesulfonyl chloride; triethylamine; In acetonitrile; at 0 ℃;

diazomethane; In diethyl ether; acetonitrile; at 0 ℃; Further stages.;
DOI:10.1021/ol990790l

Reference yield:

: 768-90-1
1-Adamantyl bromide

: 5934-69-0
1-(1-adamantyl)-2-diazo-1-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / hexane / 5 h / Cooling with ice

2: thionyl chloride / benzene / 5 h / 80 °C / Reflux

3: diethyl ether / Cooling with ice

With thionyl chloride; sulfuric acid; In diethyl ether; hexane; benzene;
DOI:10.1080/00397911.2011.622061