Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

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Chemical Name:Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate
CAS No.:122900-32-7
Molecular Formula:C₃₃H₄₀N₃O₈P*2K
Molecular Weight:715.866
Hs Code.:

Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

Synonyms:Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

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Chemical Property of Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

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Technology Process of Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

There total 5 articles about Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 122899-91-6
N--L-leucine

: 122900-32-7
Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

Guidance literature:: Multi-step reaction with 3 steps

1: 1-hydroxybenzotriazole, DCC / dimethylformamide / 10 h / 4 °C

2: H₂ / 10percent Pd/C / methanol / 760 Torr

3: aq. KOH / ethanol / 64 h

With potassium hydroxide; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00163a044

Reference yield:

: (S)-2-(Diethoxy-phosphorylamino)-4-methyl-pentanoic acid benzyl ester

: 122900-32-7
Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / methanol / 760 Torr

2: 1-hydroxybenzotriazole, DCC / dimethylformamide / 10 h / 4 °C

3: H₂ / 10percent Pd/C / methanol / 760 Torr

4: aq. KOH / ethanol / 64 h

With potassium hydroxide; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00163a044

Reference yield:

: 63779-73-7
H-Tyr(OBzl)-Phe-OMe

: 122900-32-7
Potassium; (S)-2-{(S)-3-(4-benzyloxy-phenyl)-2-[(2S,3S)-2-(ethoxy-hydroxy-phosphorylamino)-3-methyl-pentanoylamino]-propionylamino}-3-phenyl-propionate

Guidance literature:: Multi-step reaction with 3 steps

1: 1-hydroxybenzotriazole, DCC / dimethylformamide / 10 h / 4 °C

2: H₂ / 10percent Pd/C / methanol / 760 Torr

3: aq. KOH / ethanol / 64 h

With potassium hydroxide; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00163a044