C₂₂H₃₄N₂O

Base Information

• Chemical Name: C₂₂H₃₄N₂O
• CAS No.: 1331769-73-3
• Molecular Formula: C₂₂H₃₄N₂O
• Molecular Weight: 342.525
• Mol file: 1331769-73-3.mol

Synonyms:C₂₂H₃₄N₂O

Chemical Property of C₂₂H₃₄N₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₃₄N₂O

There total 8 articles about C₂₂H₃₄N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C23H34N2O2 → C22H34N2O (1331769-73-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.25h;

DOI:10.1021/acs.jafc.8b04965

Reference yield: 88.9%

N-benzyl matrinic acid benzyl ester → C22H34N2O (1331769-73-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Cooling with ice;

Reference yield:

(+)-matrine (519-02-8) → C22H34N2O (1331769-73-3)

Guidance literature:

Multi-step reaction with 5 steps

1: water; potassium hydroxide / 9 h / Reflux

2: methanol; Petroleum ether

3: potassium carbonate / dichloromethane / 20 °C

4: 3-methyl-phenol / 80 °C

5: lithium aluminium tetrahydride / tetrahydrofuran / Reflux

With lithium aluminium tetrahydride; water; potassium carbonate; 3-methyl-phenol; potassium hydroxide; In tetrahydrofuran; methanol; dichloromethane; Petroleum ether;

DOI:10.1016/j.bmcl.2011.06.071

upstream raw materials:

12-N-benzyl matrinic acid

matrinic acid diphenylmethyl ester

(+)-matrine

matrinic acid